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Divergent Allele Advantage at Human MHC Genes: Signatures of Past and Ongoing Selection
The highly polymorphic genes of the major histocompatibility complex (MHC) play a key role in adaptive immunity. Divergent allele advantage, a mechanism of balancing selection, is proposed to contribute to their exceptional polymorphism. It assumes that MHC genotypes with more divergent alleles allo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106954/ https://www.ncbi.nlm.nih.gov/pubmed/29893875 http://dx.doi.org/10.1093/molbev/msy116 |