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Glioblastoma Multiforme Involving Conus Medullaris in a Child

Primary spinal cord glioblastoma multiforme involving the conus medullaris is an uncommon entity with poor outcomes. An aggressive multimodality treatment approach has been used, but prognosis remains same. There are no guidelines for the treatment of patients with spinal glioblastoma multiforme (GB...

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Autores principales: Mansha, Muhammad Atif, Khan, Agha Muhammad Hammad, Abbasi, Ahmed Nadeem N, Tariq, Muhammad Usman U, Mushtaq, Naureen, Tariq, Maria, Waheed, Asmara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107034/
https://www.ncbi.nlm.nih.gov/pubmed/30148015
http://dx.doi.org/10.7759/cureus.2863
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author Mansha, Muhammad Atif
Khan, Agha Muhammad Hammad
Abbasi, Ahmed Nadeem N
Tariq, Muhammad Usman U
Mushtaq, Naureen
Tariq, Maria
Waheed, Asmara
author_facet Mansha, Muhammad Atif
Khan, Agha Muhammad Hammad
Abbasi, Ahmed Nadeem N
Tariq, Muhammad Usman U
Mushtaq, Naureen
Tariq, Maria
Waheed, Asmara
author_sort Mansha, Muhammad Atif
collection PubMed
description Primary spinal cord glioblastoma multiforme involving the conus medullaris is an uncommon entity with poor outcomes. An aggressive multimodality treatment approach has been used, but prognosis remains same. There are no guidelines for the treatment of patients with spinal glioblastoma multiforme (GBM). We highlight the case of a child diagnosed with conal GBM. He was treated with definitive surgery followed by adjuvant concurrent chemoradiation. After completion of treatment, he showed a temporary symptomatic improvement, but later on his condition deteriorated. We elaborate the stepwise treatment approach employed in this patient.
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spelling pubmed-61070342018-08-24 Glioblastoma Multiforme Involving Conus Medullaris in a Child Mansha, Muhammad Atif Khan, Agha Muhammad Hammad Abbasi, Ahmed Nadeem N Tariq, Muhammad Usman U Mushtaq, Naureen Tariq, Maria Waheed, Asmara Cureus Pediatrics Primary spinal cord glioblastoma multiforme involving the conus medullaris is an uncommon entity with poor outcomes. An aggressive multimodality treatment approach has been used, but prognosis remains same. There are no guidelines for the treatment of patients with spinal glioblastoma multiforme (GBM). We highlight the case of a child diagnosed with conal GBM. He was treated with definitive surgery followed by adjuvant concurrent chemoradiation. After completion of treatment, he showed a temporary symptomatic improvement, but later on his condition deteriorated. We elaborate the stepwise treatment approach employed in this patient. Cureus 2018-06-22 /pmc/articles/PMC6107034/ /pubmed/30148015 http://dx.doi.org/10.7759/cureus.2863 Text en Copyright © 2018, Mansha et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Mansha, Muhammad Atif
Khan, Agha Muhammad Hammad
Abbasi, Ahmed Nadeem N
Tariq, Muhammad Usman U
Mushtaq, Naureen
Tariq, Maria
Waheed, Asmara
Glioblastoma Multiforme Involving Conus Medullaris in a Child
title Glioblastoma Multiforme Involving Conus Medullaris in a Child
title_full Glioblastoma Multiforme Involving Conus Medullaris in a Child
title_fullStr Glioblastoma Multiforme Involving Conus Medullaris in a Child
title_full_unstemmed Glioblastoma Multiforme Involving Conus Medullaris in a Child
title_short Glioblastoma Multiforme Involving Conus Medullaris in a Child
title_sort glioblastoma multiforme involving conus medullaris in a child
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107034/
https://www.ncbi.nlm.nih.gov/pubmed/30148015
http://dx.doi.org/10.7759/cureus.2863
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