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Meckel’s Diverticulum in Crohn’s Disease Revisited: A Case of Meckel’s Diverticulitis in a Patient with Stricturing Crohn’s Disease

According to anecdotal reports in literature, encountering Meckel’s diverticulum in a patient with Crohn’s disease is not uncommon, but differentiating between the overlapping complications of Mickel’s diverticulum and the natural manifestations of Crohn’s disease can be challenging and may impact l...

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Autores principales: Kassim, Thamer, Abdussalam, Abdullah, Jenkins, Erin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107039/
https://www.ncbi.nlm.nih.gov/pubmed/30148017
http://dx.doi.org/10.7759/cureus.2865
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author Kassim, Thamer
Abdussalam, Abdullah
Jenkins, Erin
author_facet Kassim, Thamer
Abdussalam, Abdullah
Jenkins, Erin
author_sort Kassim, Thamer
collection PubMed
description According to anecdotal reports in literature, encountering Meckel’s diverticulum in a patient with Crohn’s disease is not uncommon, but differentiating between the overlapping complications of Mickel’s diverticulum and the natural manifestations of Crohn’s disease can be challenging and may impact lifelong therapy. In this report, we present a case of Meckel’s diverticulitis in a patient with stricturing ileocolonic Crohn’s disease. A 29-year-old male has been suffering from recurrent bouts of abdominal pain and diarrhea which were initially thought to be due to recurrent flares of Crohn’s disease. The patient was started on different medical regimens to control his disease, but complete remission was not achieved. He was found to have an inflamed Meckel’s diverticulum during laparotomy with sections of transmural inflammation extending into the diverticulum with absence of heterotopic mucosa. Although Meckel’s diverticulum and Crohn’s disease involve separate disease processes and different pathogenesis, several hypotheses to explain a correlation have been suggested. We believe it is important to consider the presence of an inflamed Meckel’s diverticulum in the differential diagnosis for patients with refractory Crohn’s disease who do not have an adequate response to medical therapy.
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spelling pubmed-61070392018-08-24 Meckel’s Diverticulum in Crohn’s Disease Revisited: A Case of Meckel’s Diverticulitis in a Patient with Stricturing Crohn’s Disease Kassim, Thamer Abdussalam, Abdullah Jenkins, Erin Cureus Internal Medicine According to anecdotal reports in literature, encountering Meckel’s diverticulum in a patient with Crohn’s disease is not uncommon, but differentiating between the overlapping complications of Mickel’s diverticulum and the natural manifestations of Crohn’s disease can be challenging and may impact lifelong therapy. In this report, we present a case of Meckel’s diverticulitis in a patient with stricturing ileocolonic Crohn’s disease. A 29-year-old male has been suffering from recurrent bouts of abdominal pain and diarrhea which were initially thought to be due to recurrent flares of Crohn’s disease. The patient was started on different medical regimens to control his disease, but complete remission was not achieved. He was found to have an inflamed Meckel’s diverticulum during laparotomy with sections of transmural inflammation extending into the diverticulum with absence of heterotopic mucosa. Although Meckel’s diverticulum and Crohn’s disease involve separate disease processes and different pathogenesis, several hypotheses to explain a correlation have been suggested. We believe it is important to consider the presence of an inflamed Meckel’s diverticulum in the differential diagnosis for patients with refractory Crohn’s disease who do not have an adequate response to medical therapy. Cureus 2018-06-22 /pmc/articles/PMC6107039/ /pubmed/30148017 http://dx.doi.org/10.7759/cureus.2865 Text en Copyright © 2018, Kassim et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Kassim, Thamer
Abdussalam, Abdullah
Jenkins, Erin
Meckel’s Diverticulum in Crohn’s Disease Revisited: A Case of Meckel’s Diverticulitis in a Patient with Stricturing Crohn’s Disease
title Meckel’s Diverticulum in Crohn’s Disease Revisited: A Case of Meckel’s Diverticulitis in a Patient with Stricturing Crohn’s Disease
title_full Meckel’s Diverticulum in Crohn’s Disease Revisited: A Case of Meckel’s Diverticulitis in a Patient with Stricturing Crohn’s Disease
title_fullStr Meckel’s Diverticulum in Crohn’s Disease Revisited: A Case of Meckel’s Diverticulitis in a Patient with Stricturing Crohn’s Disease
title_full_unstemmed Meckel’s Diverticulum in Crohn’s Disease Revisited: A Case of Meckel’s Diverticulitis in a Patient with Stricturing Crohn’s Disease
title_short Meckel’s Diverticulum in Crohn’s Disease Revisited: A Case of Meckel’s Diverticulitis in a Patient with Stricturing Crohn’s Disease
title_sort meckel’s diverticulum in crohn’s disease revisited: a case of meckel’s diverticulitis in a patient with stricturing crohn’s disease
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107039/
https://www.ncbi.nlm.nih.gov/pubmed/30148017
http://dx.doi.org/10.7759/cureus.2865
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