Cargando…

Update on drug development targeting parasite cysteine proteases

Detalles Bibliográficos
Autor principal:	McKerrow, James H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Viewpoints
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107105/ https://www.ncbi.nlm.nih.gov/pubmed/30138309 http://dx.doi.org/10.1371/journal.pntd.0005850

Ejemplares similares

The diverse roles of cysteine proteases in parasites and their suitability as drug targets
por: McKerrow, James H.
Publicado: (2018)

Designing Drugs for Parasitic Diseases of the Developing World
por: McKerrow, James H
Publicado: (2005)

Cysteine Protease Inhibitors Cure an Experimental Trypanosoma cruzi Infection
por: Engel, Juan C., et al.
Publicado: (1998)

Editorial: Drug Development for Parasite-Induced Diarrheal Diseases
por: Debnath, Anjan, et al.
Publicado: (2017)

A Parasite Cysteine Protease Is Key to Host Protein Degradation and Iron Acquisition
por: O'Brien, Theresa C., et al.
Publicado: (2008)

The rule of five should not impede anti-parasitic drug development
por: McKerrow, James H., et al.
Publicado: (2017)

Schistosomiasis Mansoni: Novel Chemotherapy Using a Cysteine Protease Inhibitor
por: Abdulla, Maha-Hamadien, et al.
Publicado: (2007)

SmCL3, a Gastrodermal Cysteine Protease of the Human Blood Fluke Schistosoma mansoni
por: Dvořák, Jan, et al.
Publicado: (2009)

Cysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater Planaria
por: Goupil, Louise S., et al.
Publicado: (2016)

World Class Parasites: Vol. X, Schistosomiasis
por: McKerrow, James
Publicado: (2006)

Cysteine proteases in protozoan parasites
por: Siqueira-Neto, Jair L., et al.
Publicado: (2018)

A Global Comparison of the Human and T. brucei Degradomes Gives Insights about Possible Parasite Drug Targets
por: Mashiyama, Susan T., et al.
Publicado: (2012)

Inhibitor of Cysteine Protease of Plasmodium malariae Regulates Malapains, Endogenous Cysteine Proteases of the Parasite
por: Lê, Hương Giang, et al.
Publicado: (2022)

Cysteine proteases as digestive enzymes in parasitic helminths
por: Caffrey, Conor R., et al.
Publicado: (2018)

Roles of Cysteine Proteases in Biology and Pathogenesis of Parasites
por: Yang, Nawu, et al.
Publicado: (2023)

Substrate Specificity of Cysteine Proteases Beyond the S(2) Pocket: Mutagenesis and Molecular Dynamics Investigation of Fasciola hepatica Cathepsins L
por: Corvo, Ileana, et al.
Publicado: (2018)

Protease inhibitors targeting coronavirus and filovirus entry
por: Zhou, Yanchen, et al.
Publicado: (2015)

Harnessing autophagy to fight SARS‐CoV‐2: An update in view of recent drug development efforts
por: Rein, Theo
Publicado: (2021)

Cysteine Proteases as Validated Targets for the Treatment of Neglected and Poverty-Related Parasitic Diseases
por: Ettari, Roberta
Publicado: (2023)

Gut microbiota and drug-induced liver injury: an update
por: Niu, Meng-Wei, et al.
Publicado: (2020)

The Trypanosoma cruzi Protease Cruzain Mediates Immune Evasion
por: Doyle, Patricia S., et al.
Publicado: (2011)

Delineation of Diverse Macrophage Activation Programs in Response to Intracellular Parasites and Cytokines
por: Zhang, Shuyi, et al.
Publicado: (2010)

It’s All about Those Bases: The Need for Incorporating Parasite Genetic Heterogeneity into the Development of Schistosome Vaccines
por: Gleichsner, Alyssa M., et al.
Publicado: (2015)

Implications of the COVID-19 Pandemic for the Development and Update of Clinical Practice Guidelines: Viewpoint
por: Steeb, Theresa, et al.
Publicado: (2020)

Parasite genomics—Time to think bigger
por: Talavera-López, Carlos, et al.
Publicado: (2017)

Cysteine Proteases
por: Grzonka, Zbigniew, et al.
Publicado: (2007)

WormAssay: A Novel Computer Application for Whole-Plate Motion-based Screening of Macroscopic Parasites
por: Marcellino, Chris, et al.
Publicado: (2012)

“Neuroacanthocytosis” – Overdue for a Taxonomic Update
por: Walker, Ruth H., et al.
Publicado: (2021)

Neglected Parasitic Infections and Poverty in the United States
por: Hotez, Peter J.
Publicado: (2014)

An Updated Theoretical Framework for Vocal Hyperfunction
por: Hillman, Robert E., et al.
Publicado: (2020)

Congenital Toxoplasmosis in France and the United States: One Parasite, Two Diverging Approaches
por: Peyron, Francois, et al.
Publicado: (2017)

Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions
por: De Muylder, Géraldine, et al.
Publicado: (2016)

Trypanosoma cruzi: Time for International Recognition as a Foodborne Parasite
por: Robertson, Lucy J., et al.
Publicado: (2016)

Recent updates in diagnosis and management of drug-resistant tuberculosis in India: A paradigm shift and the way ahead during the COVID-19 crisis
por: Gupta, Mansi, et al.
Publicado: (2022)

Update on the Non-Huntington's Disease Choreas with Comments on the Current Nomenclature
por: Walker, Ruth H.
Publicado: (2012)

Preclinical Alzheimer Disease Drug Development: Early Considerations Based on Phase 3 Clinical Trials
por: Hung, Anna, et al.
Publicado: (2020)

Introduction to robotics /
por: McKerrow, Phillip, 1949-
Publicado: (1991)

Update on Coronary Angiography-Based Physiology Technologies
por: Hideo-Kajita, Alexandre, et al.
Publicado: (2019)

Updates on the Latest Surgical Approach of the Aortic Stenosis
por: Geicu, Lucian, et al.
Publicado: (2021)

Gene expression patterns during adaptation of a helminth parasite to different environmental niches
por: Jolly, Emmitt R, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_c916mtkvelsifgo474g34n4j2r