Why are RNA virus mutation rates so damn high?

The high mutation rate of RNA viruses is credited with their evolvability and virulence. This Primer, however, discusses recent evidence that this is, in part, a byproduct of selection for faster genomic replication.

Detalles Bibliográficos
Autor principal: Duffy, Siobain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107253/
https://www.ncbi.nlm.nih.gov/pubmed/30102691
http://dx.doi.org/10.1371/journal.pbio.3000003
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author Duffy, Siobain
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description The high mutation rate of RNA viruses is credited with their evolvability and virulence. This Primer, however, discusses recent evidence that this is, in part, a byproduct of selection for faster genomic replication.
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spelling pubmed-61072532018-08-30 Why are RNA virus mutation rates so damn high? Duffy, Siobain PLoS Biol Primer The high mutation rate of RNA viruses is credited with their evolvability and virulence. This Primer, however, discusses recent evidence that this is, in part, a byproduct of selection for faster genomic replication. Public Library of Science 2018-08-13 /pmc/articles/PMC6107253/ /pubmed/30102691 http://dx.doi.org/10.1371/journal.pbio.3000003 Text en © 2018 Siobain Duffy http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Primer
Duffy, Siobain
Why are RNA virus mutation rates so damn high?
title Why are RNA virus mutation rates so damn high?
title_full Why are RNA virus mutation rates so damn high?
title_fullStr Why are RNA virus mutation rates so damn high?
title_full_unstemmed Why are RNA virus mutation rates so damn high?
title_short Why are RNA virus mutation rates so damn high?
title_sort why are rna virus mutation rates so damn high?
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107253/
https://www.ncbi.nlm.nih.gov/pubmed/30102691
http://dx.doi.org/10.1371/journal.pbio.3000003
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