Wdr62 is involved in female meiotic initiation via activating JNK signaling and associated with POI in humans

Meiosis is a germ cell-specific division that is indispensable for the generation of haploid gametes. However, the regulatory mechanisms of meiotic initiation remain elusive. Here, we report that the Wdr62 (WD40-repeat protein 62) is involved in meiotic initiation as a permissive factor rather than...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Qin, Yan, Qin, Yingying, Xu, Binyang, Guo, Ting, Ke, Hanni, Chen, Min, Zhang, Lianjun, Han, Feng, Li, Yaqiong, Behrens, Axel, Wang, Yaqing, Xu, Zhiheng, Chen, Zi-Jiang, Gao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107287/
https://www.ncbi.nlm.nih.gov/pubmed/30102701
http://dx.doi.org/10.1371/journal.pgen.1007463

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