Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces

Interactions of influenza A virus (IAV) with sialic acid (SIA) receptors determine viral fitness and host tropism. Binding to mucus decoy receptors and receptors on epithelial host cells is determined by a receptor-binding hemagglutinin (HA), a receptor-destroying neuraminidase (NA) and a complex in...

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Detalles Bibliográficos
Autores principales: Guo, Hongbo, Rabouw, Huib, Slomp, Anne, Dai, Meiling, van der Vegt, Floor, van Lent, Jan W. M., McBride, Ryan, Paulson, James C., de Groot, Raoul J., van Kuppeveld, Frank J. M., de Vries, Erik, de Haan, Cornelis A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107293/
https://www.ncbi.nlm.nih.gov/pubmed/30102740
http://dx.doi.org/10.1371/journal.ppat.1007233

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