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Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism

Mitochondrial dysfunction is a hallmark of metabolic diseases such as obesity, type 2 diabetes mellitus, neurodegenerative diseases, and cancers. Dysfunction occurs in part because of altered regulation of the mitochondrial pyruvate dehydrogenase complex (PDC), which acts as a central metabolic node...

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Detalles Bibliográficos
Autores principales: Park, Sungmi, Jeon, Jae-Han, Min, Byong-Keol, Ha, Chae-Myeong, Thoudam, Themis, Park, Bo-Yoon, Lee, In-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107359/
https://www.ncbi.nlm.nih.gov/pubmed/30136450
http://dx.doi.org/10.4093/dmj.2018.0101

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