KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function

Estrogen receptor alpha (ERα) is a ligand-activated nuclear receptor that directs proliferation and differentiation in selected cancer cell types including mammary-derived carcinomas. These master-regulatory functions of ERα require trans-acting elements such as the pioneer factor FOXA1 to establish...

Descripción completa

Detalles Bibliográficos
Autores principales: Gala, Kinisha, Li, Qing, Sinha, Amit, Razavi, Pedram, Dorso, Madeline, Sanchez-Vega, Francisco, Chung, Young Rock, Hendrickson, Ronald, Hsieh, James J., Berger, Michael, Schultz, Nikolaus, Pastore, Alessandro, Abdel-Wahab, Omar, Chandarlapaty, Sarat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107480/
https://www.ncbi.nlm.nih.gov/pubmed/29755131
http://dx.doi.org/10.1038/s41388-018-0273-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107480/
https://www.ncbi.nlm.nih.gov/pubmed/29755131
http://dx.doi.org/10.1038/s41388-018-0273-5

Ejemplares similares