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Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease
Those patients with perianal Crohn’s disease or ulcerative colitis experience a difficult to treat disease process with a delayed state and often inability to heal despite current therapies. The approaches currently used to treat these patients with corticosteroids, antibiotics, immunomodulators, an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107517/ https://www.ncbi.nlm.nih.gov/pubmed/30148075 http://dx.doi.org/10.5500/wjt.v8.i4.97 |
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author | Dailey, Francis E Turse, Erica P Naseer, Maliha Bragg, Jack D Tahan, Veysel |
author_facet | Dailey, Francis E Turse, Erica P Naseer, Maliha Bragg, Jack D Tahan, Veysel |
author_sort | Dailey, Francis E |
collection | PubMed |
description | Those patients with perianal Crohn’s disease or ulcerative colitis experience a difficult to treat disease process with a delayed state and often inability to heal despite current therapies. The approaches currently used to treat these patients with corticosteroids, antibiotics, immunomodulators, anti-tumor necrosis factor-α drug, and surgical repair are limited in their healing ability. This review presents all current literature since emergence in the early 2000s of stem cell therapy for patients with perianal inflammatory bowel disease and analyzes the efficacy, outcomes and safety within these studies. |
format | Online Article Text |
id | pubmed-6107517 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-61075172018-08-24 Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease Dailey, Francis E Turse, Erica P Naseer, Maliha Bragg, Jack D Tahan, Veysel World J Transplant Minireviews Those patients with perianal Crohn’s disease or ulcerative colitis experience a difficult to treat disease process with a delayed state and often inability to heal despite current therapies. The approaches currently used to treat these patients with corticosteroids, antibiotics, immunomodulators, anti-tumor necrosis factor-α drug, and surgical repair are limited in their healing ability. This review presents all current literature since emergence in the early 2000s of stem cell therapy for patients with perianal inflammatory bowel disease and analyzes the efficacy, outcomes and safety within these studies. Baishideng Publishing Group Inc 2018-08-09 2018-08-09 /pmc/articles/PMC6107517/ /pubmed/30148075 http://dx.doi.org/10.5500/wjt.v8.i4.97 Text en ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Minireviews Dailey, Francis E Turse, Erica P Naseer, Maliha Bragg, Jack D Tahan, Veysel Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease |
title | Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease |
title_full | Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease |
title_fullStr | Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease |
title_full_unstemmed | Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease |
title_short | Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease |
title_sort | review of stem cells as promising therapy for perianal disease in inflammatory bowel disease |
topic | Minireviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107517/ https://www.ncbi.nlm.nih.gov/pubmed/30148075 http://dx.doi.org/10.5500/wjt.v8.i4.97 |
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