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CTD-dependent and -independent mechanisms govern co-transcriptional capping of Pol II transcripts

Co-transcriptional capping of RNA polymerase II (Pol II) transcripts by capping enzyme proceeds orders of magnitude more efficiently than capping of free RNA. Previous studies brought to light a role for the phosphorylated Pol II carboxyl-terminal domain (CTD) in activation of co-transcriptional cap...

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Detalles Bibliográficos
Autores principales:	Noe Gonzalez, Melvin, Sato, Shigeo, Tomomori-Sato, Chieri, Conaway, Joan W., Conaway, Ronald C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107522/ https://www.ncbi.nlm.nih.gov/pubmed/30139934 http://dx.doi.org/10.1038/s41467-018-05923-w

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