Novel HDAC5-interacting motifs of Tbx3 are essential for the suppression of E-cadherin expression and for the promotion of metastasis in hepatocellular carcinoma

Tbx3, a transcriptional repressor, is essential in the organogenesis of vertebrates, stem cell self-renewal and differentiation, and the carcinogenesis of multiple tumor types. However, the mechanism by which Tbx3 participates in the metastasis of hepatocellular carcinoma (HCC) remains largely unkno...

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Detalles Bibliográficos
Autores principales: Dong, Liang, Dong, Qi, Chen, Ying, Li, Yichen, Zhang, Bao, Zhou, Fanghang, Lyu, Xiaoming, Chen, George G., Lai, Paul, Kung, Hsiang-fu, He, Ming-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107554/
https://www.ncbi.nlm.nih.gov/pubmed/30151243
http://dx.doi.org/10.1038/s41392-018-0025-6

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