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Topological motifs populate complex networks through grouped attachment

Network motifs are topological subgraph patterns that recur with statistical significance in a network. Network motifs have been widely utilized to represent important topological features for analyzing the functional properties of complex networks. While recent studies have shown the importance of...

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Detalles Bibliográficos
Autores principales: Choi, Jaejoon, Lee, Doheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107624/
https://www.ncbi.nlm.nih.gov/pubmed/30140017
http://dx.doi.org/10.1038/s41598-018-30845-4
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author Choi, Jaejoon
Lee, Doheon
author_facet Choi, Jaejoon
Lee, Doheon
author_sort Choi, Jaejoon
collection PubMed
description Network motifs are topological subgraph patterns that recur with statistical significance in a network. Network motifs have been widely utilized to represent important topological features for analyzing the functional properties of complex networks. While recent studies have shown the importance of network motifs, existing network models are not capable of reproducing real-world topological properties of network motifs, such as the frequency of network motifs and relative graphlet frequency distances. Here, we propose a new network measure and a new network model to reconstruct real-world network topologies, by incorporating our Grouped Attachment algorithm to generate networks in which closely related nodes have similar edge connections. We applied the proposed model to real-world complex networks, and the resulting constructed networks more closely reflected real-world network motif properties than did the existing models that we tested: the Erdös–Rényi, small-world, scale-free, popularity-similarity-optimization, and nonuniform popularity-similarity-optimization models. Furthermore, we adapted the preferential attachment algorithm to our model to gain scale-free properties while preserving motif properties. Our findings show that grouped attachment is one possible mechanism to reproduce network motif recurrence in real-world complex networks.
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spelling pubmed-61076242018-08-28 Topological motifs populate complex networks through grouped attachment Choi, Jaejoon Lee, Doheon Sci Rep Article Network motifs are topological subgraph patterns that recur with statistical significance in a network. Network motifs have been widely utilized to represent important topological features for analyzing the functional properties of complex networks. While recent studies have shown the importance of network motifs, existing network models are not capable of reproducing real-world topological properties of network motifs, such as the frequency of network motifs and relative graphlet frequency distances. Here, we propose a new network measure and a new network model to reconstruct real-world network topologies, by incorporating our Grouped Attachment algorithm to generate networks in which closely related nodes have similar edge connections. We applied the proposed model to real-world complex networks, and the resulting constructed networks more closely reflected real-world network motif properties than did the existing models that we tested: the Erdös–Rényi, small-world, scale-free, popularity-similarity-optimization, and nonuniform popularity-similarity-optimization models. Furthermore, we adapted the preferential attachment algorithm to our model to gain scale-free properties while preserving motif properties. Our findings show that grouped attachment is one possible mechanism to reproduce network motif recurrence in real-world complex networks. Nature Publishing Group UK 2018-08-23 /pmc/articles/PMC6107624/ /pubmed/30140017 http://dx.doi.org/10.1038/s41598-018-30845-4 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Choi, Jaejoon
Lee, Doheon
Topological motifs populate complex networks through grouped attachment
title Topological motifs populate complex networks through grouped attachment
title_full Topological motifs populate complex networks through grouped attachment
title_fullStr Topological motifs populate complex networks through grouped attachment
title_full_unstemmed Topological motifs populate complex networks through grouped attachment
title_short Topological motifs populate complex networks through grouped attachment
title_sort topological motifs populate complex networks through grouped attachment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107624/
https://www.ncbi.nlm.nih.gov/pubmed/30140017
http://dx.doi.org/10.1038/s41598-018-30845-4
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