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Instant Clue: A Software Suite for Interactive Data Visualization and Analysis

The development of modern high-throughput instrumentation and improved core facility infrastructures leads to an accumulation of large amounts of scientific data. However, for a majority of scientists the comprehensive analysis and visualization of their data goes beyond their expertise. To reduce t...

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Autores principales: Nolte, Hendrik, MacVicar, Thomas D., Tellkamp, Frederik, Krüger, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107636/
https://www.ncbi.nlm.nih.gov/pubmed/30140043
http://dx.doi.org/10.1038/s41598-018-31154-6
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author Nolte, Hendrik
MacVicar, Thomas D.
Tellkamp, Frederik
Krüger, Marcus
author_facet Nolte, Hendrik
MacVicar, Thomas D.
Tellkamp, Frederik
Krüger, Marcus
author_sort Nolte, Hendrik
collection PubMed
description The development of modern high-throughput instrumentation and improved core facility infrastructures leads to an accumulation of large amounts of scientific data. However, for a majority of scientists the comprehensive analysis and visualization of their data goes beyond their expertise. To reduce this hurdle, we developed a software suite called Instant Clue that helps scientists to visually analyze data and to gain insights into biological processes from their high-dimensional dataset. Instant Clue combines the power of visual and statistical analytics using a straight forward drag & drop approach making the software highly intuitive. Additionally, it offers a comprehensive portfolio of statistical tools for systematic analysis such as dimensional reduction, (un)-supervised learning, clustering, multi-block (omics) integration and curve fitting. Charts can be combined with high flexibility into a main figure template for direct usage in scientific publications. Even though Instant Clue was developed with the omics-sciences in mind, users can analyze any kind of data from low to high dimensional data sets. The open-source software is available for Windows and Mac OS (http://www.instantclue.uni-koeln.de) and is accompanied by a detailed video tutorial series.
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spelling pubmed-61076362018-08-28 Instant Clue: A Software Suite for Interactive Data Visualization and Analysis Nolte, Hendrik MacVicar, Thomas D. Tellkamp, Frederik Krüger, Marcus Sci Rep Article The development of modern high-throughput instrumentation and improved core facility infrastructures leads to an accumulation of large amounts of scientific data. However, for a majority of scientists the comprehensive analysis and visualization of their data goes beyond their expertise. To reduce this hurdle, we developed a software suite called Instant Clue that helps scientists to visually analyze data and to gain insights into biological processes from their high-dimensional dataset. Instant Clue combines the power of visual and statistical analytics using a straight forward drag & drop approach making the software highly intuitive. Additionally, it offers a comprehensive portfolio of statistical tools for systematic analysis such as dimensional reduction, (un)-supervised learning, clustering, multi-block (omics) integration and curve fitting. Charts can be combined with high flexibility into a main figure template for direct usage in scientific publications. Even though Instant Clue was developed with the omics-sciences in mind, users can analyze any kind of data from low to high dimensional data sets. The open-source software is available for Windows and Mac OS (http://www.instantclue.uni-koeln.de) and is accompanied by a detailed video tutorial series. Nature Publishing Group UK 2018-08-23 /pmc/articles/PMC6107636/ /pubmed/30140043 http://dx.doi.org/10.1038/s41598-018-31154-6 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Nolte, Hendrik
MacVicar, Thomas D.
Tellkamp, Frederik
Krüger, Marcus
Instant Clue: A Software Suite for Interactive Data Visualization and Analysis
title Instant Clue: A Software Suite for Interactive Data Visualization and Analysis
title_full Instant Clue: A Software Suite for Interactive Data Visualization and Analysis
title_fullStr Instant Clue: A Software Suite for Interactive Data Visualization and Analysis
title_full_unstemmed Instant Clue: A Software Suite for Interactive Data Visualization and Analysis
title_short Instant Clue: A Software Suite for Interactive Data Visualization and Analysis
title_sort instant clue: a software suite for interactive data visualization and analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107636/
https://www.ncbi.nlm.nih.gov/pubmed/30140043
http://dx.doi.org/10.1038/s41598-018-31154-6
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