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Crystal structure of human Mediator subunit MED23

The Mediator complex transduces regulatory information from enhancers to promoters and performs essential roles in the initiation of transcription in eukaryotes. Human Mediator comprises 26 subunits forming three modules termed Head, Middle and Tail. Here we present the 2.8 Å crystal structure of ME...

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Detalles Bibliográficos
Autores principales:	Monté, Didier, Clantin, Bernard, Dewitte, Frédérique, Lens, Zoé, Rucktooa, Prakash, Pardon, Els, Steyaert, Jan, Verger, Alexis, Villeret, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107663/ https://www.ncbi.nlm.nih.gov/pubmed/30140054 http://dx.doi.org/10.1038/s41467-018-05967-y

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