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Micro-Hotspots of Risk in Urban Cholera Epidemics
Targeted interventions have been delivered to neighbors of cholera cases in major epidemic responses globally despite limited evidence for the impact of such targeting. Using data from urban epidemics in Chad and Democratic Republic of the Congo, we estimate the extent of spatiotemporal zones of inc...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107744/ https://www.ncbi.nlm.nih.gov/pubmed/29757428 http://dx.doi.org/10.1093/infdis/jiy283 |
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author | Azman, Andrew S Luquero, Francisco J Salje, Henrik Mbaïbardoum, Nathan Naibei Adalbert, Ngandwe Ali, Mohammad Bertuzzo, Enrico Finger, Flavio Toure, Brahima Massing, Louis Albert Ramazani, Romain Saga, Bansaga Allan, Maya Olson, David Leglise, Jerome Porten, Klaudia Lessler, Justin |
author_facet | Azman, Andrew S Luquero, Francisco J Salje, Henrik Mbaïbardoum, Nathan Naibei Adalbert, Ngandwe Ali, Mohammad Bertuzzo, Enrico Finger, Flavio Toure, Brahima Massing, Louis Albert Ramazani, Romain Saga, Bansaga Allan, Maya Olson, David Leglise, Jerome Porten, Klaudia Lessler, Justin |
author_sort | Azman, Andrew S |
collection | PubMed |
description | Targeted interventions have been delivered to neighbors of cholera cases in major epidemic responses globally despite limited evidence for the impact of such targeting. Using data from urban epidemics in Chad and Democratic Republic of the Congo, we estimate the extent of spatiotemporal zones of increased cholera risk around cases. In both cities, we found zones of increased risk of at least 200 meters during the 5 days immediately after case presentation to a clinic. Risk was highest for those living closest to cases and diminished in time and space similarly across settings. These results provide a rational basis for rapidly delivering targeting interventions. |
format | Online Article Text |
id | pubmed-6107744 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61077442018-08-30 Micro-Hotspots of Risk in Urban Cholera Epidemics Azman, Andrew S Luquero, Francisco J Salje, Henrik Mbaïbardoum, Nathan Naibei Adalbert, Ngandwe Ali, Mohammad Bertuzzo, Enrico Finger, Flavio Toure, Brahima Massing, Louis Albert Ramazani, Romain Saga, Bansaga Allan, Maya Olson, David Leglise, Jerome Porten, Klaudia Lessler, Justin J Infect Dis Major Articles and Brief Reports Targeted interventions have been delivered to neighbors of cholera cases in major epidemic responses globally despite limited evidence for the impact of such targeting. Using data from urban epidemics in Chad and Democratic Republic of the Congo, we estimate the extent of spatiotemporal zones of increased cholera risk around cases. In both cities, we found zones of increased risk of at least 200 meters during the 5 days immediately after case presentation to a clinic. Risk was highest for those living closest to cases and diminished in time and space similarly across settings. These results provide a rational basis for rapidly delivering targeting interventions. Oxford University Press 2018-10-01 2018-05-11 /pmc/articles/PMC6107744/ /pubmed/29757428 http://dx.doi.org/10.1093/infdis/jiy283 Text en © The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Major Articles and Brief Reports Azman, Andrew S Luquero, Francisco J Salje, Henrik Mbaïbardoum, Nathan Naibei Adalbert, Ngandwe Ali, Mohammad Bertuzzo, Enrico Finger, Flavio Toure, Brahima Massing, Louis Albert Ramazani, Romain Saga, Bansaga Allan, Maya Olson, David Leglise, Jerome Porten, Klaudia Lessler, Justin Micro-Hotspots of Risk in Urban Cholera Epidemics |
title | Micro-Hotspots of Risk in Urban Cholera Epidemics |
title_full | Micro-Hotspots of Risk in Urban Cholera Epidemics |
title_fullStr | Micro-Hotspots of Risk in Urban Cholera Epidemics |
title_full_unstemmed | Micro-Hotspots of Risk in Urban Cholera Epidemics |
title_short | Micro-Hotspots of Risk in Urban Cholera Epidemics |
title_sort | micro-hotspots of risk in urban cholera epidemics |
topic | Major Articles and Brief Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107744/ https://www.ncbi.nlm.nih.gov/pubmed/29757428 http://dx.doi.org/10.1093/infdis/jiy283 |
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