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Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery
The broad substrate capacity of the intestinal oligopeptide transporter, PepT1, has made it a key target of research into drug delivery. Whilst the substrate capacity of this transporter is broad, studies have largely been limited to small peptides and peptide-like drugs. Here, we demonstrate for th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editions Scientifiques Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107785/ https://www.ncbi.nlm.nih.gov/pubmed/30006163 http://dx.doi.org/10.1016/j.ejmech.2018.06.064 |