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The Natural Agonist of Estrogen Receptor β Silibinin Plays an Immunosuppressive Role Representing a Potential Therapeutic Tool in Rheumatoid Arthritis
Estrogens, in particular 17β-estradiol (E2), have a strong influence on the immune system and also affect pathological conditions such as autoimmune diseases. The biological effects of E2 are mediated by two intracellular receptors, i.e., estrogen receptor (ER)α and ERβ, which function as ligand-act...
Autores principales: | Dupuis, Maria Luisa, Conti, Fabrizio, Maselli, Angela, Pagano, Maria Teresa, Ruggieri, Anna, Anticoli, Simona, Fragale, Alessandra, Gabriele, Lucia, Gagliardi, Maria Cristina, Sanchez, Massimo, Ceccarelli, Fulvia, Alessandri, Cristiano, Valesini, Guido, Ortona, Elena, Pierdominici, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107853/ https://www.ncbi.nlm.nih.gov/pubmed/30174672 http://dx.doi.org/10.3389/fimmu.2018.01903 |
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