Cargando…
What is the role of bronchial thermoplasty in the management of severe asthma?
Asthma is a common chronic inflammatory condition of the airways. Conventional therapy comprises inhaled corticosteroid and bronchodilators as well as trigger avoidance and management of comorbid conditions. A small group remain symptomatic despite these strategies and novel therapies have been deve...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108009/ https://www.ncbi.nlm.nih.gov/pubmed/30132377 http://dx.doi.org/10.1177/1753466618792410 |
_version_ | 1783350070972776448 |
---|---|
author | O’Reilly, Aoife Lane, Stephen |
author_facet | O’Reilly, Aoife Lane, Stephen |
author_sort | O’Reilly, Aoife |
collection | PubMed |
description | Asthma is a common chronic inflammatory condition of the airways. Conventional therapy comprises inhaled corticosteroid and bronchodilators as well as trigger avoidance and management of comorbid conditions. A small group remain symptomatic despite these strategies and novel therapies have been developed. Bronchial thermoplasty is a nonpharmacological therapy which targets airway smooth muscle to improve asthma control. Clinical trials to date have shown the efficacy and safety of bronchial thermoplasty with a persistent effect on extended follow up. Questions remain regarding the exact mechanism of action of bronchial thermoplasty, the cost effectiveness of the procedure and the ideal criteria for patient selection. |
format | Online Article Text |
id | pubmed-6108009 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-61080092018-08-27 What is the role of bronchial thermoplasty in the management of severe asthma? O’Reilly, Aoife Lane, Stephen Ther Adv Respir Dis Review Asthma is a common chronic inflammatory condition of the airways. Conventional therapy comprises inhaled corticosteroid and bronchodilators as well as trigger avoidance and management of comorbid conditions. A small group remain symptomatic despite these strategies and novel therapies have been developed. Bronchial thermoplasty is a nonpharmacological therapy which targets airway smooth muscle to improve asthma control. Clinical trials to date have shown the efficacy and safety of bronchial thermoplasty with a persistent effect on extended follow up. Questions remain regarding the exact mechanism of action of bronchial thermoplasty, the cost effectiveness of the procedure and the ideal criteria for patient selection. SAGE Publications 2018-08-22 /pmc/articles/PMC6108009/ /pubmed/30132377 http://dx.doi.org/10.1177/1753466618792410 Text en © The Author(s), 2018 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review O’Reilly, Aoife Lane, Stephen What is the role of bronchial thermoplasty in the management of severe asthma? |
title | What is the role of bronchial thermoplasty in the management of severe asthma? |
title_full | What is the role of bronchial thermoplasty in the management of severe asthma? |
title_fullStr | What is the role of bronchial thermoplasty in the management of severe asthma? |
title_full_unstemmed | What is the role of bronchial thermoplasty in the management of severe asthma? |
title_short | What is the role of bronchial thermoplasty in the management of severe asthma? |
title_sort | what is the role of bronchial thermoplasty in the management of severe asthma? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108009/ https://www.ncbi.nlm.nih.gov/pubmed/30132377 http://dx.doi.org/10.1177/1753466618792410 |
work_keys_str_mv | AT oreillyaoife whatistheroleofbronchialthermoplastyinthemanagementofsevereasthma AT lanestephen whatistheroleofbronchialthermoplastyinthemanagementofsevereasthma |