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What is the role of bronchial thermoplasty in the management of severe asthma?

Asthma is a common chronic inflammatory condition of the airways. Conventional therapy comprises inhaled corticosteroid and bronchodilators as well as trigger avoidance and management of comorbid conditions. A small group remain symptomatic despite these strategies and novel therapies have been deve...

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Detalles Bibliográficos
Autores principales: O’Reilly, Aoife, Lane, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108009/
https://www.ncbi.nlm.nih.gov/pubmed/30132377
http://dx.doi.org/10.1177/1753466618792410
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author O’Reilly, Aoife
Lane, Stephen
author_facet O’Reilly, Aoife
Lane, Stephen
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description Asthma is a common chronic inflammatory condition of the airways. Conventional therapy comprises inhaled corticosteroid and bronchodilators as well as trigger avoidance and management of comorbid conditions. A small group remain symptomatic despite these strategies and novel therapies have been developed. Bronchial thermoplasty is a nonpharmacological therapy which targets airway smooth muscle to improve asthma control. Clinical trials to date have shown the efficacy and safety of bronchial thermoplasty with a persistent effect on extended follow up. Questions remain regarding the exact mechanism of action of bronchial thermoplasty, the cost effectiveness of the procedure and the ideal criteria for patient selection.
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spelling pubmed-61080092018-08-27 What is the role of bronchial thermoplasty in the management of severe asthma? O’Reilly, Aoife Lane, Stephen Ther Adv Respir Dis Review Asthma is a common chronic inflammatory condition of the airways. Conventional therapy comprises inhaled corticosteroid and bronchodilators as well as trigger avoidance and management of comorbid conditions. A small group remain symptomatic despite these strategies and novel therapies have been developed. Bronchial thermoplasty is a nonpharmacological therapy which targets airway smooth muscle to improve asthma control. Clinical trials to date have shown the efficacy and safety of bronchial thermoplasty with a persistent effect on extended follow up. Questions remain regarding the exact mechanism of action of bronchial thermoplasty, the cost effectiveness of the procedure and the ideal criteria for patient selection. SAGE Publications 2018-08-22 /pmc/articles/PMC6108009/ /pubmed/30132377 http://dx.doi.org/10.1177/1753466618792410 Text en © The Author(s), 2018 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Review
O’Reilly, Aoife
Lane, Stephen
What is the role of bronchial thermoplasty in the management of severe asthma?
title What is the role of bronchial thermoplasty in the management of severe asthma?
title_full What is the role of bronchial thermoplasty in the management of severe asthma?
title_fullStr What is the role of bronchial thermoplasty in the management of severe asthma?
title_full_unstemmed What is the role of bronchial thermoplasty in the management of severe asthma?
title_short What is the role of bronchial thermoplasty in the management of severe asthma?
title_sort what is the role of bronchial thermoplasty in the management of severe asthma?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108009/
https://www.ncbi.nlm.nih.gov/pubmed/30132377
http://dx.doi.org/10.1177/1753466618792410
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