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Surgical treatment outcome of giant cell tumor of distal ulna: En bloc resection vs. curettage and bone graft

Background: Giant cell tumor (GCT) of the bone is a benign neoplasm with local aggressive behavior. Distal ulna is a very rare place for GCT. Published studies have mainly focused on case reports, and thus there is no consistent treatment strategy for this tumor at this location. This retrospective...

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Autores principales: Jamshidi, Khodamorad, Bahrabadi, Mehrdad, Bagherifard, Abolfazl, Mohamadpour, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iran University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108277/
https://www.ncbi.nlm.nih.gov/pubmed/30159295
http://dx.doi.org/10.14196/mjiri.32.44
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author Jamshidi, Khodamorad
Bahrabadi, Mehrdad
Bagherifard, Abolfazl
Mohamadpour, Mehdi
author_facet Jamshidi, Khodamorad
Bahrabadi, Mehrdad
Bagherifard, Abolfazl
Mohamadpour, Mehdi
author_sort Jamshidi, Khodamorad
collection PubMed
description Background: Giant cell tumor (GCT) of the bone is a benign neoplasm with local aggressive behavior. Distal ulna is a very rare place for GCT. Published studies have mainly focused on case reports, and thus there is no consistent treatment strategy for this tumor at this location. This retrospective study was conducted to evaluate the oncological and functional results of 2 different surgical treatment methods for GCT in distal ulna. Methods: In this study, 9 patients with GCT of distal ulna were followed after surgical treatment of GCT of distal ulna. Of the patients, 2 had local recurrence after surgery in other hospitals and 7 had primarily been admitted to our hospital. Four patients, all with grade 2 Enneking and Campanacci’s classification, were treated by extended curettage and bone grafting, while 5 patients with grade 3 were managed by distal ulnar resection. Minimum follow-up time was 24 months. Results: Patients with grade 3 GCT of distal ulna, who had extended curettage, had a local recurrence up to one year after surgery. Local recurrence was never seen in those with grade 3 disease with resection or in those with grade 2 disease with extended curettage as the treatment of GCT in this location. Conclusion: Based on our study, which is the largest cohort of GCT of distal ulna, extended curettage, and en bloc resection can be suggested as valuable methods of treatment for grades 2 and 3 tumors, respectively.
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spelling pubmed-61082772018-08-29 Surgical treatment outcome of giant cell tumor of distal ulna: En bloc resection vs. curettage and bone graft Jamshidi, Khodamorad Bahrabadi, Mehrdad Bagherifard, Abolfazl Mohamadpour, Mehdi Med J Islam Repub Iran Original Article Background: Giant cell tumor (GCT) of the bone is a benign neoplasm with local aggressive behavior. Distal ulna is a very rare place for GCT. Published studies have mainly focused on case reports, and thus there is no consistent treatment strategy for this tumor at this location. This retrospective study was conducted to evaluate the oncological and functional results of 2 different surgical treatment methods for GCT in distal ulna. Methods: In this study, 9 patients with GCT of distal ulna were followed after surgical treatment of GCT of distal ulna. Of the patients, 2 had local recurrence after surgery in other hospitals and 7 had primarily been admitted to our hospital. Four patients, all with grade 2 Enneking and Campanacci’s classification, were treated by extended curettage and bone grafting, while 5 patients with grade 3 were managed by distal ulnar resection. Minimum follow-up time was 24 months. Results: Patients with grade 3 GCT of distal ulna, who had extended curettage, had a local recurrence up to one year after surgery. Local recurrence was never seen in those with grade 3 disease with resection or in those with grade 2 disease with extended curettage as the treatment of GCT in this location. Conclusion: Based on our study, which is the largest cohort of GCT of distal ulna, extended curettage, and en bloc resection can be suggested as valuable methods of treatment for grades 2 and 3 tumors, respectively. Iran University of Medical Sciences 2018-06-01 /pmc/articles/PMC6108277/ /pubmed/30159295 http://dx.doi.org/10.14196/mjiri.32.44 Text en © 2018 Iran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Jamshidi, Khodamorad
Bahrabadi, Mehrdad
Bagherifard, Abolfazl
Mohamadpour, Mehdi
Surgical treatment outcome of giant cell tumor of distal ulna: En bloc resection vs. curettage and bone graft
title Surgical treatment outcome of giant cell tumor of distal ulna: En bloc resection vs. curettage and bone graft
title_full Surgical treatment outcome of giant cell tumor of distal ulna: En bloc resection vs. curettage and bone graft
title_fullStr Surgical treatment outcome of giant cell tumor of distal ulna: En bloc resection vs. curettage and bone graft
title_full_unstemmed Surgical treatment outcome of giant cell tumor of distal ulna: En bloc resection vs. curettage and bone graft
title_short Surgical treatment outcome of giant cell tumor of distal ulna: En bloc resection vs. curettage and bone graft
title_sort surgical treatment outcome of giant cell tumor of distal ulna: en bloc resection vs. curettage and bone graft
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108277/
https://www.ncbi.nlm.nih.gov/pubmed/30159295
http://dx.doi.org/10.14196/mjiri.32.44
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