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African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat
The African trypanosome, Trypanosoma brucei spp., is a paradigm for antigenic variation, the orchestrated alteration of cell surface molecules to evade host immunity. The parasite elicits robust antibody-mediated immune responses to its Variant Surface Glycoprotein (VSG) coat, but evades immune clea...
Autores principales: | Pinger, Jason, Nešić, Dragana, Ali, Liaqat, Aresta-Branco, Francisco, Lilic, Mirjana, Chowdhury, Shanin, Kim, Hee-Sook, Verdi, Joseph, Raper, Jayne, Ferguson, Michael A. J., Papavasiliou, F. Nina, Stebbins, C. Erec |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108419/ https://www.ncbi.nlm.nih.gov/pubmed/29988048 http://dx.doi.org/10.1038/s41564-018-0187-6 |
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