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Extensive impact of non-antibiotic drugs on human gut bacteria

A few commonly used non-antibiotic drugs have recently been associated with changes in gut microbiome composition, but the extent of this phenomenon is unknown. We screened >1000 marketed drugs against 40 representative gut bacterial strains, and found that 24% of the drugs with human targets, in...

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Detalles Bibliográficos
Autores principales: Maier, Lisa, Pruteanu, Mihaela, Kuhn, Michael, Zeller, Georg, Telzerow, Anja, Anderson, Exene Erin, Brochado, Ana Rita, Fernandez, Keith Conrad, Dose, Hitomi, Mori, Hirotada, Patil, Kiran Raosaheb, Bork, Peer, Typas, Athanasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108420/
https://www.ncbi.nlm.nih.gov/pubmed/29555994
http://dx.doi.org/10.1038/nature25979