Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger

As a powerful tool for fast and precise genome editing, the CRISPR/Cas9 system has been applied in filamentous fungi to improve the efficiency of genome alteration. However, the method of delivering guide RNA (gRNA) remains a bottleneck in performing CRISPR mutagenesis in Aspergillus species. Here w...

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Detalles Bibliográficos
Autores principales: Song, Letian, Ouedraogo, Jean-Paul, Kolbusz, Magdalena, Nguyen, Thi Truc Minh, Tsang, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108506/
https://www.ncbi.nlm.nih.gov/pubmed/30142205
http://dx.doi.org/10.1371/journal.pone.0202868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108506/
https://www.ncbi.nlm.nih.gov/pubmed/30142205
http://dx.doi.org/10.1371/journal.pone.0202868

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