Overexpression of Slit2 improves function of the paravascular pathway in the aging mouse brain

Aging is associated with impairment of the paravascular pathway caused by the activation of astrocytes and depolarization of protein aquaporin-4 (AQP4) water channels, resulting in the accumulation of protein waste, including amyloid β (Aβ), in the brain parenchyma. The secreted glycoprotein slit gu...

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Detalles Bibliográficos
Autores principales: Li, Ge, He, Xiaofei, Li, Hang, Wu, Yu'e, Guan, Yalun, Liu, Shuhua, Jia, Huanhuan, Li, Yunfeng, Wang, Lijing, Huang, Ren, Pei, Zhong, Lan, Yue, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108881/
https://www.ncbi.nlm.nih.gov/pubmed/30085336
http://dx.doi.org/10.3892/ijmm.2018.3802

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