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Networking chemical robots for reaction multitasking

The development of the internet of things has led to an explosion in the number of networked devices capable of control and computing. However, whilst common place in remote sensing, these approaches have not impacted chemistry due to difficulty in developing systems flexible enough for experimental...

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Autores principales: Caramelli, Dario, Salley, Daniel, Henson, Alon, Camarasa, Gerardo Aragon, Sharabi, Salah, Keenan, Graham, Cronin, Leroy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109044/
https://www.ncbi.nlm.nih.gov/pubmed/30143646
http://dx.doi.org/10.1038/s41467-018-05828-8
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author Caramelli, Dario
Salley, Daniel
Henson, Alon
Camarasa, Gerardo Aragon
Sharabi, Salah
Keenan, Graham
Cronin, Leroy
author_facet Caramelli, Dario
Salley, Daniel
Henson, Alon
Camarasa, Gerardo Aragon
Sharabi, Salah
Keenan, Graham
Cronin, Leroy
author_sort Caramelli, Dario
collection PubMed
description The development of the internet of things has led to an explosion in the number of networked devices capable of control and computing. However, whilst common place in remote sensing, these approaches have not impacted chemistry due to difficulty in developing systems flexible enough for experimental data collection. Herein we present a simple and affordable (<$500) chemistry capable robot built with a standard set of hardware and software protocols that can be networked to coordinate many chemical experiments in real time. We demonstrate how multiple processes can be done with two internet-connected robots collaboratively, exploring a set of azo-coupling reactions in a fraction of time needed for a single robot, as well as encoding and decoding information into a network of oscillating reactions. The system can also be used to assess the reproducibility of chemical reactions and discover new reaction outcomes using game playing to explore a chemical space.
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spelling pubmed-61090442018-08-27 Networking chemical robots for reaction multitasking Caramelli, Dario Salley, Daniel Henson, Alon Camarasa, Gerardo Aragon Sharabi, Salah Keenan, Graham Cronin, Leroy Nat Commun Article The development of the internet of things has led to an explosion in the number of networked devices capable of control and computing. However, whilst common place in remote sensing, these approaches have not impacted chemistry due to difficulty in developing systems flexible enough for experimental data collection. Herein we present a simple and affordable (<$500) chemistry capable robot built with a standard set of hardware and software protocols that can be networked to coordinate many chemical experiments in real time. We demonstrate how multiple processes can be done with two internet-connected robots collaboratively, exploring a set of azo-coupling reactions in a fraction of time needed for a single robot, as well as encoding and decoding information into a network of oscillating reactions. The system can also be used to assess the reproducibility of chemical reactions and discover new reaction outcomes using game playing to explore a chemical space. Nature Publishing Group UK 2018-08-24 /pmc/articles/PMC6109044/ /pubmed/30143646 http://dx.doi.org/10.1038/s41467-018-05828-8 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Caramelli, Dario
Salley, Daniel
Henson, Alon
Camarasa, Gerardo Aragon
Sharabi, Salah
Keenan, Graham
Cronin, Leroy
Networking chemical robots for reaction multitasking
title Networking chemical robots for reaction multitasking
title_full Networking chemical robots for reaction multitasking
title_fullStr Networking chemical robots for reaction multitasking
title_full_unstemmed Networking chemical robots for reaction multitasking
title_short Networking chemical robots for reaction multitasking
title_sort networking chemical robots for reaction multitasking
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109044/
https://www.ncbi.nlm.nih.gov/pubmed/30143646
http://dx.doi.org/10.1038/s41467-018-05828-8
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