The Antihelminthic Niclosamide Inhibits Cancer Stemness, Extracellular Matrix Remodeling, and Metastasis through Dysregulation of the Nuclear β-catenin/c-Myc axis in OSCC

Niclosamide is an oral chlorinated salicylanilide antihelminthic agent with potential anticancer activity suggested in several cancer types, however, its anticancer action and likely molecular mechanism in malignant oral cells remain unclear. In the present study, we demonstrated that ALDH+ human or...

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Detalles Bibliográficos
Autores principales: Wang, Lin-Hong, Xu, Mei, Fu, Luo-Qin, Chen, Xiao-Yi, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109047/
https://www.ncbi.nlm.nih.gov/pubmed/30143678
http://dx.doi.org/10.1038/s41598-018-30692-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109047/
https://www.ncbi.nlm.nih.gov/pubmed/30143678
http://dx.doi.org/10.1038/s41598-018-30692-3

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