Cargando…
PSD-95-nNOS Coupling Regulates Contextual Fear Extinction in the Dorsal CA3
Fear extinction depends on N-methyl-D-aspartate glutamate receptors (NMDARs) and brain-derived neurotrophic factor (BDNF) activation in the limbic system. However, postsynaptic density-95 (PSD-95) and neuronal nitric oxide synthase (nNOS) coupling, the downstream signaling of NMDARs activation, obst...
Autores principales: | Cai, Cheng-Yun, Chen, Chen, Zhou, Ying, Han, Zhou, Qin, Cheng, Cao, Bo, Tao, Yan, Bian, Xin-Lan, Lin, Yu-Hui, Chang, Lei, Wu, Hai-Yin, Luo, Chun-Xia, Zhu, Dong-Ya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109109/ https://www.ncbi.nlm.nih.gov/pubmed/30143658 http://dx.doi.org/10.1038/s41598-018-30899-4 |
Ejemplares similares
-
Phosphorylation of PSD-95 at serine 73 in dCA1 is required for extinction of contextual fear
por: Ziółkowska, Magdalena, et al.
Publicado: (2023) -
PSD95 and nNOS interaction as a novel molecular target to modulate conditioned fear: relevance to PTSD
por: Li, L.- P., et al.
Publicado: (2018) -
Tau induces PSD95-nNOS uncoupling and neurovascular dysfunction independent of neurodegeneration
por: Park, Laibaik, et al.
Publicado: (2020) -
4335 Role of PSD95 and nNOS interaction in gene regulation following fear conditioning and implications for molecular mechanisms underlying PTSD
por: Patel, Jheel, et al.
Publicado: (2020) -
77822 PSD95-nNOS interaction alters the basolateral amygdala transcriptome following fear conditioning: implications for molecular mechanisms underlying PTSD
por: Patel, Jheel, et al.
Publicado: (2021)