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A Plasmodium berghei sporozoite-based vaccination platform against human malaria

There is a pressing need for safe and highly effective Plasmodium falciparum (Pf) malaria vaccines. The circumsporozoite protein (CS), expressed on sporozoites and during early hepatic stages, is a leading target vaccine candidate, but clinical efficacy has been modest so far. Conversely, whole-spor...

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Detalles Bibliográficos
Autores principales:	Mendes, António M., Machado, Marta, Gonçalves-Rosa, Nataniel, Reuling, Isaie J., Foquet, Lander, Marques, Cláudia, Salman, Ahmed M., Yang, Annie S. P., Moser, Kara A., Dwivedi, Ankit, Hermsen, Cornelus C., Jiménez-Díaz, Belén, Viera, Sara, Santos, Jorge M., Albuquerque, Inês, Bhatia, Sangeeta N., Bial, John, Angulo-Barturen, Iñigo, Silva, Joana C., Leroux-Roels, Geert, Janse, Chris J., Khan, Shahid M., Mota, Maria M., Sauerwein, Robert W., Prudêncio, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109154/ https://www.ncbi.nlm.nih.gov/pubmed/30155278 http://dx.doi.org/10.1038/s41541-018-0068-2

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