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Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota
Mammalian gut microbiota are integral to host health. However, how this association began remains unclear. We show that in basal chordates the gut space is radially compartmentalized into a luminal part where food microbes pass and an almost axenic peripheral part, defined by membranous delamination...
Autores principales: | Nakashima, Keisuke, Kimura, Satoshi, Ogawa, Yu, Watanabe, Soichi, Soma, Satoshi, Kaneko, Toyoji, Yamada, Lixy, Sawada, Hitoshi, Tung, Che-Huang, Lu, Tsai-Ming, Yu, Jr-Kai, Villar-Briones, Alejandro, Kikuchi, Sakura, Satoh, Noriyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109156/ https://www.ncbi.nlm.nih.gov/pubmed/30143642 http://dx.doi.org/10.1038/s41467-018-05884-0 |
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