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Lack of cyclin D3 induces skeletal muscle fiber-type shifting, increased endurance performance and hypermetabolism
The mitogen-induced D-type cyclins (D1, D2 and D3) are regulatory subunits of the cyclin-dependent kinases CDK4 and CDK6 that drive progression through the G1 phase of the cell cycle. In skeletal muscle, cyclin D3 plays a unique function in controlling the proliferation/differentiation balance of my...
Autores principales: | Giannattasio, Silvia, Giacovazzo, Giacomo, Bonato, Agnese, Caruso, Carla, Luvisetto, Siro, Coccurello, Roberto, Caruso, Maurizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109157/ https://www.ncbi.nlm.nih.gov/pubmed/30143714 http://dx.doi.org/10.1038/s41598-018-31090-5 |
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