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Validation of new transmission detector transmission factors for online dosimetry: an experimental study

BACKGROUND: The demand for dose verification during treatment has risen with the increasing use of intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) in modern radiation therapy. This study aims to validate the transmission factors of a new transmission detector...

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Autores principales: Park, So-Yeon, Park, Jong Min, Kim, Jung-in, Lee, Sungyoung, Choi, Chang Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109263/
https://www.ncbi.nlm.nih.gov/pubmed/30143012
http://dx.doi.org/10.1186/s13014-018-1106-y
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author Park, So-Yeon
Park, Jong Min
Kim, Jung-in
Lee, Sungyoung
Choi, Chang Heon
author_facet Park, So-Yeon
Park, Jong Min
Kim, Jung-in
Lee, Sungyoung
Choi, Chang Heon
author_sort Park, So-Yeon
collection PubMed
description BACKGROUND: The demand for dose verification during treatment has risen with the increasing use of intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) in modern radiation therapy. This study aims to validate the transmission factors of a new transmission detector, the Dolphin online monitoring system (IBA Dosimetry, Schwarzenbruck, Germany), for clinical use. METHODS: The transmission factors of the Dolphin detector were evaluated using 6 MV, 6 flattening filter free (FFF), 10 MV, and 10 FFF clinical beams from a TrueBeam STx linear accelerator system. Two-dimensional (2D) dose distributions were measured through portal dosimetry with and without Dolphin to derive the transmission factors. The measurements were performed using 10 IMRT and 10 VMAT treatment plans. The transmission factors were calculated using a non-negative least squares problem solver for the 2D dose matrix. Normalized plans were generated using the derived transmission factors. Patient-specific quality assurance with normalized plans was performed using portal dosimetry and an ArcCheck detector to verify the transmission factors. The gamma passing rates were calculated for the 2%/2 mm and 1%/1 mm criteria. RESULTS: The transmission factors for the 6 MV, 6 FFF, 10 MV, and 10 FFF beams, were 0.878, 0.824, 0.913, and 0.883, respectively. The average dose difference between the original plan without Dolphin and the normalized plan with Dolphin was less than 1.8% for all measurements. The mean passing rates of the gamma evaluation were 98.1 ± 2.1 and 82.9 ± 12.6 for the 2%/2 mm and 1%/1 mm criteria, respectively, for portal dosimetry of the original plan. In the case of the portal dosimetry of the normalized plan, the mean passing rates of the gamma evaluation were 97.2 ± 2.8 and 79.1 ± 14.8 for the 2%/2 mm and 1%/1 mm criteria, respectively. CONCLUSIONS: The Dolphin detector can be used for online dosimetry when valid transmission factors are applied to the clinical plan.
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spelling pubmed-61092632018-08-29 Validation of new transmission detector transmission factors for online dosimetry: an experimental study Park, So-Yeon Park, Jong Min Kim, Jung-in Lee, Sungyoung Choi, Chang Heon Radiat Oncol Research BACKGROUND: The demand for dose verification during treatment has risen with the increasing use of intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) in modern radiation therapy. This study aims to validate the transmission factors of a new transmission detector, the Dolphin online monitoring system (IBA Dosimetry, Schwarzenbruck, Germany), for clinical use. METHODS: The transmission factors of the Dolphin detector were evaluated using 6 MV, 6 flattening filter free (FFF), 10 MV, and 10 FFF clinical beams from a TrueBeam STx linear accelerator system. Two-dimensional (2D) dose distributions were measured through portal dosimetry with and without Dolphin to derive the transmission factors. The measurements were performed using 10 IMRT and 10 VMAT treatment plans. The transmission factors were calculated using a non-negative least squares problem solver for the 2D dose matrix. Normalized plans were generated using the derived transmission factors. Patient-specific quality assurance with normalized plans was performed using portal dosimetry and an ArcCheck detector to verify the transmission factors. The gamma passing rates were calculated for the 2%/2 mm and 1%/1 mm criteria. RESULTS: The transmission factors for the 6 MV, 6 FFF, 10 MV, and 10 FFF beams, were 0.878, 0.824, 0.913, and 0.883, respectively. The average dose difference between the original plan without Dolphin and the normalized plan with Dolphin was less than 1.8% for all measurements. The mean passing rates of the gamma evaluation were 98.1 ± 2.1 and 82.9 ± 12.6 for the 2%/2 mm and 1%/1 mm criteria, respectively, for portal dosimetry of the original plan. In the case of the portal dosimetry of the normalized plan, the mean passing rates of the gamma evaluation were 97.2 ± 2.8 and 79.1 ± 14.8 for the 2%/2 mm and 1%/1 mm criteria, respectively. CONCLUSIONS: The Dolphin detector can be used for online dosimetry when valid transmission factors are applied to the clinical plan. BioMed Central 2018-08-24 /pmc/articles/PMC6109263/ /pubmed/30143012 http://dx.doi.org/10.1186/s13014-018-1106-y Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Park, So-Yeon
Park, Jong Min
Kim, Jung-in
Lee, Sungyoung
Choi, Chang Heon
Validation of new transmission detector transmission factors for online dosimetry: an experimental study
title Validation of new transmission detector transmission factors for online dosimetry: an experimental study
title_full Validation of new transmission detector transmission factors for online dosimetry: an experimental study
title_fullStr Validation of new transmission detector transmission factors for online dosimetry: an experimental study
title_full_unstemmed Validation of new transmission detector transmission factors for online dosimetry: an experimental study
title_short Validation of new transmission detector transmission factors for online dosimetry: an experimental study
title_sort validation of new transmission detector transmission factors for online dosimetry: an experimental study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109263/
https://www.ncbi.nlm.nih.gov/pubmed/30143012
http://dx.doi.org/10.1186/s13014-018-1106-y
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