Interaction between the microbiome and TP53 in human lung cancer

BACKGROUND: Lung cancer is the leading cancer diagnosis worldwide and the number one cause of cancer deaths. Exposure to cigarette smoke, the primary risk factor in lung cancer, reduces epithelial barrier integrity and increases susceptibility to infections. Herein, we hypothesize that somatic mutat...

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Detalles Bibliográficos
Autores principales: Greathouse, K. Leigh, White, James R., Vargas, Ashely J., Bliskovsky, Valery V., Beck, Jessica A., von Muhlinen, Natalia, Polley, Eric C., Bowman, Elise D., Khan, Mohammed A., Robles, Ana I., Cooks, Tomer, Ryan, Bríd M., Padgett, Noah, Dzutsev, Amiran H., Trinchieri, Giorgio, Pineda, Marbin A., Bilke, Sven, Meltzer, Paul S., Hokenstad, Alexis N., Stickrod, Tricia M., Walther-Antonio, Marina R., Earl, Joshua P., Mell, Joshua C., Krol, Jaroslaw E., Balashov, Sergey V., Bhat, Archana S., Ehrlich, Garth D., Valm, Alex, Deming, Clayton, Conlan, Sean, Oh, Julia, Segre, Julie A., Harris, Curtis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109311/
https://www.ncbi.nlm.nih.gov/pubmed/30143034
http://dx.doi.org/10.1186/s13059-018-1501-6

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