ALDH1A3 upregulation and spontaneous metastasis formation is associated with acquired chemoresistance in colorectal cancer cells

BACKGROUND: Efficiency of colorectal carcinoma treatment by chemotherapy is diminished as the resistance develops over time in patients. The same holds true for 5-fluorouracil, the drug used in first line chemotherapy of colorectal carcinoma. METHODS: Chemoresistant derivative of HT-29 cells was pre...

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Detalles Bibliográficos
Autores principales: Durinikova, Erika, Kozovska, Zuzana, Poturnajova, Martina, Plava, Jana, Cierna, Zuzana, Babelova, Andrea, Bohovic, Roman, Schmidtova, Silvia, Tomas, Miroslav, Kucerova, Lucia, Matuskova, Miroslava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109326/
https://www.ncbi.nlm.nih.gov/pubmed/30143021
http://dx.doi.org/10.1186/s12885-018-4758-y

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