Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus

ABSTRACT: Three new heptelidic acid derivatives (1–3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscop...

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Detalles Bibliográficos
Autores principales: Liu, Li, Han, Jun-Jie, Xu, Tian-Shun, Liu, Rui-Xing, Bao, Li, Liu, Hong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109445/
https://www.ncbi.nlm.nih.gov/pubmed/29790088
http://dx.doi.org/10.1007/s13659-018-0168-8
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author Liu, Li
Han, Jun-Jie
Xu, Tian-Shun
Liu, Rui-Xing
Bao, Li
Liu, Hong-Wei
author_facet Liu, Li
Han, Jun-Jie
Xu, Tian-Shun
Liu, Rui-Xing
Bao, Li
Liu, Hong-Wei
author_sort Liu, Li
collection PubMed
description ABSTRACT: Three new heptelidic acid derivatives (1–3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopic data. The biosynthetic origin of compounds 1–5 was postulated. Compounds 1–5 exhibited no antibacterial activity against Staphylococcus aureus and Escherichia coli at the dose of 100 μM. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13659-018-0168-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-61094452018-09-05 Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus Liu, Li Han, Jun-Jie Xu, Tian-Shun Liu, Rui-Xing Bao, Li Liu, Hong-Wei Nat Prod Bioprospect Original Article ABSTRACT: Three new heptelidic acid derivatives (1–3) including two new dimeric esters and two known heptelidic acid analogues (4 and 5) were isolated from the solid culture of mushroom Lentinellus ursinus. The structures of new compounds were confirmed by the analysis of NMR and HRESIMS spectroscopic data. The biosynthetic origin of compounds 1–5 was postulated. Compounds 1–5 exhibited no antibacterial activity against Staphylococcus aureus and Escherichia coli at the dose of 100 μM. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13659-018-0168-8) contains supplementary material, which is available to authorized users. Springer Singapore 2018-05-22 /pmc/articles/PMC6109445/ /pubmed/29790088 http://dx.doi.org/10.1007/s13659-018-0168-8 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Liu, Li
Han, Jun-Jie
Xu, Tian-Shun
Liu, Rui-Xing
Bao, Li
Liu, Hong-Wei
Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title_full Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title_fullStr Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title_full_unstemmed Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title_short Three New Heptelidic Acid Derivatives from the Culture of Mushroom Lentinellus ursinus
title_sort three new heptelidic acid derivatives from the culture of mushroom lentinellus ursinus
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109445/
https://www.ncbi.nlm.nih.gov/pubmed/29790088
http://dx.doi.org/10.1007/s13659-018-0168-8
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