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Overcoming P-Glycoprotein-Mediated Multidrug Resistance in Colorectal Cancer: Potential Reversal Agents among Herbal Medicines

OBJECTIVES: Multidrug resistance (MDR) is the major reason for the failure of chemotherapy in colorectal cancer (CRC), and the primary determinant of MDR in CRC patients is active drug efflux owing to overexpression of P-glycoprotein (P-gp) in cancer tissues. Despite research efforts to overcome P-g...

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Detalles Bibliográficos
Autores principales:	Lee, Gayoung, Joung, Jin-Yong, Cho, Jung-Hyo, Son, Chang-Gue, Lee, Namhun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109522/ https://www.ncbi.nlm.nih.gov/pubmed/30158992 http://dx.doi.org/10.1155/2018/3412074

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