The Rare Anaphylaxis-Associated FcγRIIa3 Exhibits Distinct Characteristics From the Canonical FcγRIIa1

FcγRIIa is an activating FcγR, unique to humans and non-human primates. It induces antibody-dependent proinflammatory responses and exists predominantly as FcγRIIa1. A unique splice variant, we designated FcγRIIa3, has been reported to be associated with anaphylactic reactions to intravenous immunog...

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Detalles Bibliográficos
Autores principales: Anania, Jessica C., Trist, Halina M., Palmer, Catherine S., Tan, Peck Szee, Kouskousis, Betty P., Chenoweth, Alicia M., Kent, Stephen J., Mackay, Graham A., Hoi, Alberta, Koelmeyer, Rachel, Slade, Charlotte, Bryant, Vanessa L., Hodgkin, Philip D., Aui, Pei Mun, van Zelm, Menno C., Wines, Bruce D., Hogarth, P. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109644/
https://www.ncbi.nlm.nih.gov/pubmed/30177930
http://dx.doi.org/10.3389/fimmu.2018.01809

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