The Nrf2-Antioxidant Response Element Signaling Pathway Controls Fibrosis and Autoimmunity in Scleroderma

Systemic sclerosis (SSc) is an autoimmune disease with fibrosis of the skin and internal organs and vascular alterations. Dysregulations in the oxidant/antioxidant balance are known to be a major factor in the pathogenesis of the disease. Indeed, reactive oxygen species (ROS) trigger neoepitopes lea...

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Detalles Bibliográficos
Autores principales: Kavian, Niloufar, Mehlal, Souad, Jeljeli, Mohamed, Saidu, Nathaniel Edward Bennett, Nicco, Carole, Cerles, Olivier, Chouzenoux, Sandrine, Cauvet, Anne, Camus, Claire, Ait-Djoudi, Mehdi, Chéreau, Christiane, Kerdine-Römer, Saadia, Allanore, Yannick, Batteux, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109691/
https://www.ncbi.nlm.nih.gov/pubmed/30177933
http://dx.doi.org/10.3389/fimmu.2018.01896

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