Cargando…
Enhancing Lysosomal Activation Restores Neural Stem Cell Function During Aging
Adult neurogenesis supports cognitive and sensory functions in mammals and is significantly reduced with age. Quiescent neural stem cells are the source of new neurons in the adult brain and emerging evidence suggests that the failure of these cells to activate and re-enter the cell cycle is largely...
Autores principales: | Audesse, Amanda J, Webb, Ashley E |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109844/ https://www.ncbi.nlm.nih.gov/pubmed/30158826 http://dx.doi.org/10.1177/1179069518795874 |
Ejemplares similares
-
FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells
por: Audesse, Amanda J., et al.
Publicado: (2019) -
Adult neural stem cell behavior underlying constitutive and restorative neurogenesis in zebrafish
por: Barbosa, Joana S., et al.
Publicado: (2016) -
Genetic, Epigenetic, and Metabolic Maintenance of Neural Stem Cells During Aging
por: Webb, Ashley
Publicado: (2020) -
New mechanism of metformin action mediated by lysosomal presenilin enhancer 2
por: Sugawara, Kenji, et al.
Publicado: (2022) -
FOXO3 regulates a common genomic program in aging and glioblastoma stem cells
por: Audesse, Amanda J., et al.
Publicado: (2021)