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Pharmacokinetics and Bioavailability Study of Monocrotaline in Mouse Blood by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry

BACKGROUND AND AIMS: The present study aimed to develop a simple and sensitive method for quantitative determination of monocrotaline (MCT) in mouse blood employing ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometry (UPLC-ESI/MS/MS) using rhynchophylline as an i...

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Detalles Bibliográficos
Autores principales: Chen, Lianguo, Zhang, Bin, Liu, Jinlai, Fan, Zhehua, Weng, Ziwei, Geng, Peiwu, Wang, Xianqin, Lin, Guanyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110008/
https://www.ncbi.nlm.nih.gov/pubmed/30186850
http://dx.doi.org/10.1155/2018/1578643