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Factors that Correlate with Poor Glycemic Control in Type 2 Diabetes Mellitus Patients with Complications

OBJECTIVES: Inadequate glycemic control amongst patients with Type 2 diabetes mellitus (T2DM) indicates a major public health problem and a significant risk factor for the progression and complications caused by diabetes. Glycemic control is the main therapeutic objective for the prevention of organ...

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Autores principales: Haghighatpanah, Mohammad, Nejad, Amir Sasan Mozaffari, Haghighatpanah, Maryam, Thunga, Girish, Mallayasamy, Surulivelrajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Centers for Disease Control and Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110332/
https://www.ncbi.nlm.nih.gov/pubmed/30159222
http://dx.doi.org/10.24171/j.phrp.2018.9.4.05
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author Haghighatpanah, Mohammad
Nejad, Amir Sasan Mozaffari
Haghighatpanah, Maryam
Thunga, Girish
Mallayasamy, Surulivelrajan
author_facet Haghighatpanah, Mohammad
Nejad, Amir Sasan Mozaffari
Haghighatpanah, Maryam
Thunga, Girish
Mallayasamy, Surulivelrajan
author_sort Haghighatpanah, Mohammad
collection PubMed
description OBJECTIVES: Inadequate glycemic control amongst patients with Type 2 diabetes mellitus (T2DM) indicates a major public health problem and a significant risk factor for the progression and complications caused by diabetes. Glycemic control is the main therapeutic objective for the prevention of organ damage and other complications arising from diabetes. METHODS: This was a retrospective observational study of T2DM patients with complications, who were aged 40 years and older. The study was conducted retrospectively on medical records (in-patient and out-patient) obtained from a South Indian teaching hospital, Manipal, India. The patients included in the study had fasting blood sugar, postprandial blood sugar and HbA1c measured at least twice during follow-ups the previous year. Patients’ HbA1c levels were categorized into good control ≤7% (≤53mmol/mol), and poor control >7% (>53mmol/mol), and patients’ characteristics were analyzed. RESULTS: A total of 657 patients were included in the study. The mean age was 59.67 (SD = 9.617) years, with 152 (23.1%) females and 505 (76.9%) males, and 514 (78.2%) patients had poor glycemic control. Most of the patients were on insulin mono-therapy [n = 271 (42.1%)], about a third of the patients were on combination therapy that included an oral hypoglycemic agent and insulin [n = 236 (36.6%)]. Patients with a history of more than 10 years of diabetes [n = 293 (44.6%)], had a family history of diabetes [n = 256 (39%)] and obesity [n = 95 (14.5%)], all had poor glycemic control. CONCLUSION: This present study indicated a significant association of gender (female), age, high-density lipoprotein level, duration of diabetes and type of medication, with poor glycemic control in T2DM patients that had secondary medical complications.
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spelling pubmed-61103322018-08-29 Factors that Correlate with Poor Glycemic Control in Type 2 Diabetes Mellitus Patients with Complications Haghighatpanah, Mohammad Nejad, Amir Sasan Mozaffari Haghighatpanah, Maryam Thunga, Girish Mallayasamy, Surulivelrajan Osong Public Health Res Perspect Original Article OBJECTIVES: Inadequate glycemic control amongst patients with Type 2 diabetes mellitus (T2DM) indicates a major public health problem and a significant risk factor for the progression and complications caused by diabetes. Glycemic control is the main therapeutic objective for the prevention of organ damage and other complications arising from diabetes. METHODS: This was a retrospective observational study of T2DM patients with complications, who were aged 40 years and older. The study was conducted retrospectively on medical records (in-patient and out-patient) obtained from a South Indian teaching hospital, Manipal, India. The patients included in the study had fasting blood sugar, postprandial blood sugar and HbA1c measured at least twice during follow-ups the previous year. Patients’ HbA1c levels were categorized into good control ≤7% (≤53mmol/mol), and poor control >7% (>53mmol/mol), and patients’ characteristics were analyzed. RESULTS: A total of 657 patients were included in the study. The mean age was 59.67 (SD = 9.617) years, with 152 (23.1%) females and 505 (76.9%) males, and 514 (78.2%) patients had poor glycemic control. Most of the patients were on insulin mono-therapy [n = 271 (42.1%)], about a third of the patients were on combination therapy that included an oral hypoglycemic agent and insulin [n = 236 (36.6%)]. Patients with a history of more than 10 years of diabetes [n = 293 (44.6%)], had a family history of diabetes [n = 256 (39%)] and obesity [n = 95 (14.5%)], all had poor glycemic control. CONCLUSION: This present study indicated a significant association of gender (female), age, high-density lipoprotein level, duration of diabetes and type of medication, with poor glycemic control in T2DM patients that had secondary medical complications. Korea Centers for Disease Control and Prevention 2018-08 /pmc/articles/PMC6110332/ /pubmed/30159222 http://dx.doi.org/10.24171/j.phrp.2018.9.4.05 Text en Copyright ©2018, Korea Centers for Disease Control and Prevention http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Article
Haghighatpanah, Mohammad
Nejad, Amir Sasan Mozaffari
Haghighatpanah, Maryam
Thunga, Girish
Mallayasamy, Surulivelrajan
Factors that Correlate with Poor Glycemic Control in Type 2 Diabetes Mellitus Patients with Complications
title Factors that Correlate with Poor Glycemic Control in Type 2 Diabetes Mellitus Patients with Complications
title_full Factors that Correlate with Poor Glycemic Control in Type 2 Diabetes Mellitus Patients with Complications
title_fullStr Factors that Correlate with Poor Glycemic Control in Type 2 Diabetes Mellitus Patients with Complications
title_full_unstemmed Factors that Correlate with Poor Glycemic Control in Type 2 Diabetes Mellitus Patients with Complications
title_short Factors that Correlate with Poor Glycemic Control in Type 2 Diabetes Mellitus Patients with Complications
title_sort factors that correlate with poor glycemic control in type 2 diabetes mellitus patients with complications
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110332/
https://www.ncbi.nlm.nih.gov/pubmed/30159222
http://dx.doi.org/10.24171/j.phrp.2018.9.4.05
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