Chemoproteomic identification of molecular targets of antifungal prototypes, thiosemicarbazide and a camphene derivative of thiosemicarbazide, in Paracoccidioides brasiliensis

Paracoccidioidomycosis (PCM) is a neglected human systemic disease caused by species of the genus Paracoccidioides. The disease attacks the host’s lungs and may disseminate to many other organs. Treatment involves amphotericin B, sulfadiazine, trimethoprim-sulfamethoxazole, itraconazole, ketoconazol...

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Detalles Bibliográficos
Autores principales: Borba, Joyce Villa Verde Bastos, Tauhata, Sinji Borges Ferreira, de Oliveira, Cecília Maria Alves, Ferreira Marques, Monique, Bailão, Alexandre Melo, Soares, Célia Maria de Almeida, Pereira, Maristela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110461/
https://www.ncbi.nlm.nih.gov/pubmed/30148835
http://dx.doi.org/10.1371/journal.pone.0201948

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