Exposure to nicotine-derived nitrosamine ketone and arecoline synergistically facilitates tumor aggressiveness via overexpression of epidermal growth factor receptor and its downstream signaling in head and neck squamous cell carcinoma

Long-term nicotine-derived nitrosamine ketone (NNK) and arecoline exposure promotes carcinogenesis and head and neck squamous cell carcinoma (HNSCC) progression, although most associated data on the two were analyzed individually. The molecular mechanisms underlying tumor progression associated with...

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Detalles Bibliográficos
Autores principales: Yang, Shih-Hsien, Lee, Tsai-Yu, Ho, Chun An, Yang, Chin-Yuh, Huang, Wen-Yen, Lin, Yu-Chun, Nieh, Shin, Lin, Yaoh-Shiang, Chen, Su-Feng, Lin, Fu-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110482/
https://www.ncbi.nlm.nih.gov/pubmed/30148841
http://dx.doi.org/10.1371/journal.pone.0201267

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