The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs

While the human genome is pervasively transcribed, <2% of the human genome is transcribed into protein-coding mRNAs, leaving most of the transcripts as noncoding RNAs, such as microRNAs and long-noncoding RNAs (lncRNAs), which are critical components of epigenetic regulation. lncRNAs are emerging...

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Detalles Bibliográficos
Autores principales: Zeng, Zongyue, Huang, Bo, Huang, Shifeng, Zhang, Ruyi, Yan, Shujuan, Yu, Xinyi, Shu, Yi, Zhao, Chen, Lei, Jiayan, Zhang, Wenwen, Yang, Chao, Wu, Ke, Wu, Ying, An, Liping, Ji, Xiaojuan, Gong, Cheng, Yuan, Chengfu, Zhang, Linghuan, Liu, Wei, Feng, Yixiao, Zhang, Bo, Dai, Zhengyu, Shen, Yi, Wang, Xi, Luo, Wenping, Haydon, Rex C., Luu, Hue H., Zhou, Lan, Reid, Russell R., He, Tong-Chuan, Wu, Xingye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110536/
https://www.ncbi.nlm.nih.gov/pubmed/30159383
http://dx.doi.org/10.1016/j.gendis.2018.02.001

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