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Particularités radiologiques de la tuberculose pulmonaire à microscopie positive au Service de Pneumologie du Centre Hospitalier National Universitaire de FANN (CHNUF), Dakar (Sénégal)
This study aimed to determine the radiological features of microscopy-positive pulmonary tuberculosis (TB). We conducted a retrospective study, analyzing radiographical imaging of patients with microscopy-positive pulmonary tuberculosis between 15 November 2015 and 15 March 2016. The medical records...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110565/ https://www.ncbi.nlm.nih.gov/pubmed/30167049 http://dx.doi.org/10.11604/pamj.2018.30.21.14208 |
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author | Kombila, Ulrich Davy Kane, Yacine Dia Mbaye, Fatimata Bintou Rassoule Diouf, Ndeye Fatou Ka, Waly Touré, Nafissatou Oumar |
author_facet | Kombila, Ulrich Davy Kane, Yacine Dia Mbaye, Fatimata Bintou Rassoule Diouf, Ndeye Fatou Ka, Waly Touré, Nafissatou Oumar |
author_sort | Kombila, Ulrich Davy |
collection | PubMed |
description | This study aimed to determine the radiological features of microscopy-positive pulmonary tuberculosis (TB). We conducted a retrospective study, analyzing radiographical imaging of patients with microscopy-positive pulmonary tuberculosis between 15 November 2015 and 15 March 2016. The medical records of 66 patients meeting the inclusion criteria were selected, 81.8% of which belonged to men. The average age of patients was 37.5 ± 14.9 years. Patients had variable parenchymal lesions dominated by infiltrated lesions in 84.8% (CI 95%; 73.9-92.4%) of cases, followed by alveolar syndrome in 68.2% (CI95%; 55.5-79.1%) of cases. Lesions were extensive in 71.2% (CI 95%; 58.7-81.7%) of cases and bilateral in 45.4% (CI 95%; 31.1-58.1%) of cases. These radiological abnormalities occurred in 52.2% (CI 95%; 36.9 - 67.1%) of cases in undernourished patients. In 22.7% (CI 95%; 13.3-34.7%) of cases, these lesions were secondary to an episode of pulmonary tuberculosis; 34.8% (IC95; 23.5 - 47.5%) of patients were regular tobacco smokers consuming, on average, 17 tobacco packs per year (±11.3). TB recurrences were more frequent in patients with a history of smoking versus non-smokers (26.1% versus 20.9%, p < 0.42 respectively). HIV-1 serology test was positive in 7.6% of cases. This study highlights the importance of suspecting pulmonary tuberculosis in young undernourished patients, having a history of smoking, with infiltrated lesions associated or not with cavitary lesions on radiographic examination and living in TB epidemic area. |
format | Online Article Text |
id | pubmed-6110565 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-61105652018-08-30 Particularités radiologiques de la tuberculose pulmonaire à microscopie positive au Service de Pneumologie du Centre Hospitalier National Universitaire de FANN (CHNUF), Dakar (Sénégal) Kombila, Ulrich Davy Kane, Yacine Dia Mbaye, Fatimata Bintou Rassoule Diouf, Ndeye Fatou Ka, Waly Touré, Nafissatou Oumar Pan Afr Med J Case Series This study aimed to determine the radiological features of microscopy-positive pulmonary tuberculosis (TB). We conducted a retrospective study, analyzing radiographical imaging of patients with microscopy-positive pulmonary tuberculosis between 15 November 2015 and 15 March 2016. The medical records of 66 patients meeting the inclusion criteria were selected, 81.8% of which belonged to men. The average age of patients was 37.5 ± 14.9 years. Patients had variable parenchymal lesions dominated by infiltrated lesions in 84.8% (CI 95%; 73.9-92.4%) of cases, followed by alveolar syndrome in 68.2% (CI95%; 55.5-79.1%) of cases. Lesions were extensive in 71.2% (CI 95%; 58.7-81.7%) of cases and bilateral in 45.4% (CI 95%; 31.1-58.1%) of cases. These radiological abnormalities occurred in 52.2% (CI 95%; 36.9 - 67.1%) of cases in undernourished patients. In 22.7% (CI 95%; 13.3-34.7%) of cases, these lesions were secondary to an episode of pulmonary tuberculosis; 34.8% (IC95; 23.5 - 47.5%) of patients were regular tobacco smokers consuming, on average, 17 tobacco packs per year (±11.3). TB recurrences were more frequent in patients with a history of smoking versus non-smokers (26.1% versus 20.9%, p < 0.42 respectively). HIV-1 serology test was positive in 7.6% of cases. This study highlights the importance of suspecting pulmonary tuberculosis in young undernourished patients, having a history of smoking, with infiltrated lesions associated or not with cavitary lesions on radiographic examination and living in TB epidemic area. The African Field Epidemiology Network 2018-05-09 /pmc/articles/PMC6110565/ /pubmed/30167049 http://dx.doi.org/10.11604/pamj.2018.30.21.14208 Text en © Ulrich Davy Kombila et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Series Kombila, Ulrich Davy Kane, Yacine Dia Mbaye, Fatimata Bintou Rassoule Diouf, Ndeye Fatou Ka, Waly Touré, Nafissatou Oumar Particularités radiologiques de la tuberculose pulmonaire à microscopie positive au Service de Pneumologie du Centre Hospitalier National Universitaire de FANN (CHNUF), Dakar (Sénégal) |
title | Particularités radiologiques de la tuberculose pulmonaire à microscopie positive au Service de Pneumologie du Centre Hospitalier National Universitaire de FANN (CHNUF), Dakar (Sénégal) |
title_full | Particularités radiologiques de la tuberculose pulmonaire à microscopie positive au Service de Pneumologie du Centre Hospitalier National Universitaire de FANN (CHNUF), Dakar (Sénégal) |
title_fullStr | Particularités radiologiques de la tuberculose pulmonaire à microscopie positive au Service de Pneumologie du Centre Hospitalier National Universitaire de FANN (CHNUF), Dakar (Sénégal) |
title_full_unstemmed | Particularités radiologiques de la tuberculose pulmonaire à microscopie positive au Service de Pneumologie du Centre Hospitalier National Universitaire de FANN (CHNUF), Dakar (Sénégal) |
title_short | Particularités radiologiques de la tuberculose pulmonaire à microscopie positive au Service de Pneumologie du Centre Hospitalier National Universitaire de FANN (CHNUF), Dakar (Sénégal) |
title_sort | particularités radiologiques de la tuberculose pulmonaire à microscopie positive au service de pneumologie du centre hospitalier national universitaire de fann (chnuf), dakar (sénégal) |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110565/ https://www.ncbi.nlm.nih.gov/pubmed/30167049 http://dx.doi.org/10.11604/pamj.2018.30.21.14208 |
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