A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure

Insufficient or dysregulated energy metabolism may underlie diverse inherited and degenerative diseases, cancer, and even aging itself. ATP is the central energy carrier in cells, but critical pathways for regulating ATP levels are not systematically understood. We combined a pooled clustered regula...

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Detalles Bibliográficos
Autores principales: Mendelsohn, Bryce A., Bennett, Neal K., Darch, Maxwell A., Yu, Katharine, Nguyen, Mai K., Pucciarelli, Daniela, Nelson, Maxine, Horlbeck, Max A., Gilbert, Luke A., Hyun, William, Kampmann, Martin, Nakamura, Jean L., Nakamura, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110572/
https://www.ncbi.nlm.nih.gov/pubmed/30148842
http://dx.doi.org/10.1371/journal.pbio.2004624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110572/
https://www.ncbi.nlm.nih.gov/pubmed/30148842
http://dx.doi.org/10.1371/journal.pbio.2004624

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