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Population Pharmacokinetics and Pharmacodynamics of Dexmedetomidine in Children Undergoing Ambulatory Surgery

BACKGROUND: Dexmedetomidine (DEX) is an α-2 adrenergic agonist with sedative and analgesic properties. Although not approved for pediatric use by the Food and Drug Administration, DEX is increasingly used in pediatric anesthesia and critical care. However, very limited information is available regar...

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Detalles Bibliográficos
Autores principales:	Pérez-Guillé, María-Gabriela, Toledo-López, Alejandra, Rivera-Espinosa, Liliana, Alemon-Medina, Radames, Murata, Chiharu, Lares-Asseff, Ismael, Chávez-Pacheco, Juan Luis, Gómez-Garduño, Josefina, Zamora Gutiérrez, Ana-Lilia, Orozco-Galicia, Claudia, Ramírez-Morales, Karina, Lugo-Goytia, Gustavo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2018
Materias:	Pediatric Anesthesiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110617/ https://www.ncbi.nlm.nih.gov/pubmed/29782406 http://dx.doi.org/10.1213/ANE.0000000000003413

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