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A Survival Metadata Analysis Responsive Tool (SMART) for web-based analysis of patient survival and risk
Health information systems contain extensive amounts of patient data. Information relevant to public health and individuals’ medical histories are both available. In clinical research, the prediction of patient survival rates and identification of prognosis factors are major challenges. To alleviate...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110739/ https://www.ncbi.nlm.nih.gov/pubmed/30150756 http://dx.doi.org/10.1038/s41598-018-31290-z |
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author | Chu, Yuan-Chia Kuo, Wen-Tsung Cheng, Yuan-Ren Lee, Chung-Yuan Shiau, Cheng-Ying Tarng, Der-Cherng Lai, Feipei |
author_facet | Chu, Yuan-Chia Kuo, Wen-Tsung Cheng, Yuan-Ren Lee, Chung-Yuan Shiau, Cheng-Ying Tarng, Der-Cherng Lai, Feipei |
author_sort | Chu, Yuan-Chia |
collection | PubMed |
description | Health information systems contain extensive amounts of patient data. Information relevant to public health and individuals’ medical histories are both available. In clinical research, the prediction of patient survival rates and identification of prognosis factors are major challenges. To alleviate the difficulties related to these factors, Metadata Utilities was developed to help researchers manage column definitions and information such as import/query/generator Metadata files. These utilities also include an automatic update mechanism to ensure consistency between the data and parameters of the batch produced in the conversion procedure. Survival Metadata Analysis Responsive Tool (SMART) provides a comprehensive set of statistical tests that are easy to understand, including support for analyzing nominal variables, ordinal variables, interval variables or ratio variables as means, standard deviations, maximum values, minimum values, and percentages. In this article, the development of a raw data source and transfer mechanism, Extract-Transform-Load (ETL), is described for data cleansing, extraction, transformation and loading. We also built a handy method for data presentation, which can be customized to the trial design. As demonstrated here, SMART is useful for risk-adjusted baseline cohort and randomized controlled trials. |
format | Online Article Text |
id | pubmed-6110739 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-61107392018-08-30 A Survival Metadata Analysis Responsive Tool (SMART) for web-based analysis of patient survival and risk Chu, Yuan-Chia Kuo, Wen-Tsung Cheng, Yuan-Ren Lee, Chung-Yuan Shiau, Cheng-Ying Tarng, Der-Cherng Lai, Feipei Sci Rep Article Health information systems contain extensive amounts of patient data. Information relevant to public health and individuals’ medical histories are both available. In clinical research, the prediction of patient survival rates and identification of prognosis factors are major challenges. To alleviate the difficulties related to these factors, Metadata Utilities was developed to help researchers manage column definitions and information such as import/query/generator Metadata files. These utilities also include an automatic update mechanism to ensure consistency between the data and parameters of the batch produced in the conversion procedure. Survival Metadata Analysis Responsive Tool (SMART) provides a comprehensive set of statistical tests that are easy to understand, including support for analyzing nominal variables, ordinal variables, interval variables or ratio variables as means, standard deviations, maximum values, minimum values, and percentages. In this article, the development of a raw data source and transfer mechanism, Extract-Transform-Load (ETL), is described for data cleansing, extraction, transformation and loading. We also built a handy method for data presentation, which can be customized to the trial design. As demonstrated here, SMART is useful for risk-adjusted baseline cohort and randomized controlled trials. Nature Publishing Group UK 2018-08-27 /pmc/articles/PMC6110739/ /pubmed/30150756 http://dx.doi.org/10.1038/s41598-018-31290-z Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Chu, Yuan-Chia Kuo, Wen-Tsung Cheng, Yuan-Ren Lee, Chung-Yuan Shiau, Cheng-Ying Tarng, Der-Cherng Lai, Feipei A Survival Metadata Analysis Responsive Tool (SMART) for web-based analysis of patient survival and risk |
title | A Survival Metadata Analysis Responsive Tool (SMART) for web-based analysis of patient survival and risk |
title_full | A Survival Metadata Analysis Responsive Tool (SMART) for web-based analysis of patient survival and risk |
title_fullStr | A Survival Metadata Analysis Responsive Tool (SMART) for web-based analysis of patient survival and risk |
title_full_unstemmed | A Survival Metadata Analysis Responsive Tool (SMART) for web-based analysis of patient survival and risk |
title_short | A Survival Metadata Analysis Responsive Tool (SMART) for web-based analysis of patient survival and risk |
title_sort | survival metadata analysis responsive tool (smart) for web-based analysis of patient survival and risk |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110739/ https://www.ncbi.nlm.nih.gov/pubmed/30150756 http://dx.doi.org/10.1038/s41598-018-31290-z |
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