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A catalogue of somatic NRF2 gain-of-function mutations in cancer
Identification and characterization of somatic mutations in cancer have important prognostication and treatment implications. Genes encoding the Nuclear factor (erythroid-derived 2)-like 2 (NRF2) transcription factor and its negative regulator, Kelch-like ECH-associated protein 1 (KEAP1), are freque...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110754/ https://www.ncbi.nlm.nih.gov/pubmed/30150714 http://dx.doi.org/10.1038/s41598-018-31281-0 |