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Defining the architecture of KPC-2 Carbapenemase: identifying allosteric networks to fight antibiotics resistance

The rise of multi-drug resistance in bacterial pathogens is one of the grand challenges facing medical science. A major concern is the speed of development of β-lactamase-mediated resistance in Gram-negative species, thus putting at risk the efficacy of the most recently approved antibiotics and inh...

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Detalles Bibliográficos
Autores principales:	Galdadas, Ioannis, Lovera, Silvia, Pérez-Hernández, Guillermo, Barnes, Melissa D., Healy, Jess, Afsharikho, Hamidreza, Woodford, Neil, Bonomo, Robert A., Gervasio, Francesco L., Haider, Shozeb
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110804/ https://www.ncbi.nlm.nih.gov/pubmed/30150677 http://dx.doi.org/10.1038/s41598-018-31176-0

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