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Distinct systemic microbiome and microbial translocation are associated with plasma level of anti-CD4 autoantibody in HIV infection

Microbial signals have been linked to autoantibody induction. Recently, we found that purified anti-CD4 autoantibodies from the plasma of chronic HIV-1-infected patients under viral-suppressed antiretroviral therapy (ART) play a pathologic role in poor CD4+ T cell recovery. The purpose of the study...

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Detalles Bibliográficos
Autores principales: Xu, Wanli, Luo, Zhenwu, Alekseyenko, Alexander V., Martin, Lisa, Wan, Zhuang, Ling, Binhua, Qin, Zhiqiang, Heath, Sonya L., Maas, Kendra, Cong, Xiaomei, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110826/
https://www.ncbi.nlm.nih.gov/pubmed/30150778
http://dx.doi.org/10.1038/s41598-018-31116-y

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